Evoke - Model eVox - Brain Health System
The eVox Brain Health System takes qEEG technology that has been used for decades in a laboratory setting and brings it into the physician’s office. With easy data collection right in your practice, eVox delivers well-established, reliable, and stable brain health biomarkers that can aid in diagnosis of cognitive disorders. We didn’t create the science, we perfected it for clinical use.
Computational EEG head maps are a visual representation of the difference in activity between a patient’s brain and a standardized database. eVox physicians complete onboarding training and have free access to ongoing clinical education so they can learn to recognize various head map patterns to facilitate diagnosis1,2.
Performance during a go/no-go task reflects a patient’s ability to perform daily tasks effectively. Reaction time, reaction time variability, omission errors, and commission errors give insight to cognitive status and behavioral functioning11-13.
To help you hone in on non-neurodegenerative causes of cognitive impairment, eVox provides computerized administration of PHQ-9, GAD-7, PCL-C, PSC-17, and DSM-5 Level 1 Cross-Cutting Symptom Measure.
According to the Alzheimer’s Association, over 70 million people in the US are at risk of Alzheimer’s disease and cognitive decline14. The eVox Brain Health System was developed to help identify the underlying causes of cognitive impairment, while there is still time to treat.
The current standard practice is to diagnose Alzheimer’s as a syndrome, meaning physicians base their diagnosis on the clinical consequences of the disease (i.e., the symptoms). But research shows that 20 years or more before symptoms appear, the brain changes that are associated with Alzheimer’s disease begin15. And, according to The Lancet Neurology, dementia could be prevented or delayed for 40% of patients – the key is early detection and intervention16.
The FINGER Study was the first randomized controlled trial showing that it’s possible to prevent cognitive decline using a multi-domain lifestyle intervention17. Results highlight the value of addressing multiple dementia risk factors (like dietary changes, exercise, cognitive training, and vascular risk monitoring) as a strategy to protect brain health, promote overall health and functioning, and reduce the risk of developing new chronic diseases.
Historically, physicians have been limited by the tools available to detect early signs of cognitive changes. The eVox System helps rectify that. Functional biomarkers measured by computational EEG and event-related potentials give insight to how the brain itself is working and are detectable even prior to symptom onset3,18. Measuring these biomarkers with the eVox Brain Health System assists physicians in the identification of at-risk patients so that appropriate treatment interventions may be implemented before it’s too late.
Our latest R&D efforts have been on developing an Artificial Intelligence (AI) biomarker for Alzheimer’s disease diagnosis. We’re currently conducting an IRB approved study, using eVox to measure EEG & ERP biomarkers for 300 patients with cognitive impairment. This dataset, along with our existing database of 60,000 EEG reports, will be used to train Machine-Learning models.
The ultimate goal? Develop an AI algorithm capable of diagnosing AD based on EEG/ERP data alone, with sensitivity and specificity levels near 100%. In partnership with the Pacific Neuroscience Institute Brain Health Center, an outpatient clinic of the Providence Saint John’s Health Center in Santa Monica, CA, we are currently enrolling subjects.
eVox helps fulfill the American Academy of Neurology’s recommendation of annual screening of patients 65+ for cognitive concerns 1.
You don’t need to solely rely on patients’ self-reported symptoms. Track brain health over time with objective EEG/ERP biomarkers.
Cognitive changes can be related to many different disorders like depression, anxiety, TBI, PTSD, ADHD, and more. eVox is designed to help you discover the root cause.
Elevating your standard of cognitive careThe eVox Brain Health System offers an easy-to-administer cognitive assessment to help PCPs identify the root cause of cognitive concerns—without relying on subjective, self-reported symptoms. eVox Reports are clear, insightful, and don’t require visual inspection of raw EEG data. eVox is easy to integrate into a clinical practice and helps physicians:
- Perform differential diagnosis
- Develop personalized treatment plans in-house
- Triage patients with cognitive impairment
- Track treatment effects and/or disease progression
- Monitor physiological aging at annual wellness exams
A new tool for the modern neurologist
The eVox Brain Health System performs computational EEG. Also called qEEG, this is a type of functional neuroimaging that can yield objective neurophysiological biomarkers related to cognitive impairment, with sensitivity upwards of 90% according to a 2018 study2. This means eVox isn’t designed to replace the standard EEG in many neurology offices. Instead, it is intended to help you diagnose cognitive disorders, track cognitive status, and monitor disease progression. eVox can help you:
- Accelerate timeline to diagnosis
- Observe treatment effects and/or disease progression
- Monitor physiological aging and track cognitive status
- Access eVox Reports as well as EDF+ files
Brain health scans made easy
COLLECT DATA
eVox is small, portable, and used right in your office.
DOWNLOAD REPORT
Download eVox Reports from your web portal. Not yet familiar with how to read them? We provide free onboarding, ongoing clinical education, and consultations with clinical experts on staff.
HELP DEVELOP A DIAGNOSIS
Use brain-based biomarkers in conjunction with your clinical work-up to help you make a more informed and objective diagnosis.
The eVox Brain Heath System helps physicians assess:
BRAIN HEALTH
qEEG and LORETA imaging
BRAIN PROCESSING SPEED
Event-related potentials (ERPs)
BEHAVIORAL PERFORMANCE
Neuropsychological testing
MENTAL HEALTH
Computerized standardized questionnaires
Big data for big science
At Evoke Neuroscience, we are dedicated to addressing the world`s most critical brain health issues. That means partnering with industry and academic researchers alike to accelerate the translational research that will help patients achieve better health outcomes.
As one of our data partners, you`ll have access to 60,000+ standardized EEG datasets to help tackle your big science questions. Whether you are working on training machine-learning algorithms for improved diagnostics, or advancing the frontier of functional brain mapping, let us provide the rich and robust data you need.
Gender, age, handedness, medications
19-lead EEG, 5 minutes eyes open plus 5 minutes eyes closed. Absolute power, 2-30 Hz (10-20 International System)
P3a, P3b, and visual N100
20 minutes, 3-lead
Reaction time, reaction time variability, omission and commission errors
Categorized by domain – memory, affect, sensory, motor, executive/attention, and word fluency