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TauroLock - Catheter Lock Solution
If you are looking for a catheter lock solution with both an antimicrobial and anticoagulant effect, we recommend TauroLock™. On this site, you can find detailed information about the product, its active ingredients, and application.
TauroLock™ has been approved for instillation into all CVCs. As a bactericidal and fungicidal lock solution, it prevents the formation of a biofilm. Patients thus remain protected from catheter-related infections and occlusion.
We recommend TauroLock™ for all vascular access devides (VADs) in parenteral nutrition, oncology, and – as an alternative to TauroLock™-HEP500 and TauroLock™-U25.000 – in dialysis.
The two active ingredients of TauroLock™ are taurolidine and 4 % citrate. Taurolidine has a broad antimicrobial activity (incl. MRSA and VRE) against gram-positive and gram-negative bacteria and fungi (e.g. Candida). Citrate works as an anticoagulant, which means it helps to maintain an adequate flow rate within the catheter.
In-between treatment sessions (e.g. dialysis, chemotherapy, parental nutrition), TauroLock™ is instilled into the saline-flushed access system. Please note that medical staff must check the filling volume of the respective catheter or port system.
Taurolidine-based lock solutions such as TauroLock™ are recommended in national and international guidelines. Generally speaking, this product may be used for central-venous catheters (CVC) in three different contexts:
Contraindications
There are some cases in which patients should not use TauroLock™:
- The patient has displayed allergic reactions to either citrate or taurolidine.
- The patient is currently taking medication which has proven incompatible with either citrate or taurolidine.
Safety
Before using the device, you need to aspirate TauroLock™ with a syringe and then flush the VAD with saline. If aspiration is not possible, you may also flush out the solution with saline. Should TauroLock™ inadvertently enter the blood stream, it will quickly degrade into the amino acid taurine. Slow flushing is therefore clinically tolerable. Do not flush lock solutions in infants and children less than two years of age.
Package Sizes
If you would like to purchase TauroLock™, there are two options available:
- single dose: ampoules of 3 ml or 5 ml (10 ampoules per box)
- multiple dose: vials of 10 ml (100 vials per box)
Storage & Transport
TauroLock™ must be stored at temperatures of 15 °C to 30 °C. Please note that you must not freeze TauroLock™ under any circumstances.