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Combines Synthetic Biology & 3D-Bioprinting

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HUMAN TISSUE IS COMPLEX - SO IS THE CHALLENGE TO BIOFABRICATE IT. The building blocks of life consist of highly specialized cells and a complex extracellular matrix… … organized in highly structured micro-units…  that together, perform the vital functions of a living organism.
Most popular related searches
  • 4 conflicting key requirements
  • high-resolution
  • multiple cell types & materials
  • human like extracellular matrix
  • large volumes and high speed

Bioinks
We develop our own application-tailored bioinks via synthetic biology and chemical engineering.

3D Bioprinting
We invented multi- material stereolitho-graphic bioprinting and own the complete tech stack of proprietary hardware, software and process engineering.

Tissue Engineering
We leverage world leading know-how in tissue engineering, with a track record of stereolithographic bioprinting various vital mini-organs with multiple materials and cell types.

  • Tailor made Bioinks - the implantable ECM
  • Cellbricks converts a digital, high resolution model of the tissue into a stack of slices for each material to be printed.
  • A high resolution UV projector projects the slice image onto the surface of the print, immersed in bio-ink. The bio-ink solidifies into a thin layer of ECM with embedded cells.
  • The print is dipped into the next bio-ink to add a second material as specified by the corresponding slice image. More materials can be added after the same method.
  • In the finished print, multiple cell types and matrices are arranged in a complex 3D structure, added layer by layer.
WE MASTER TISSUE ENGINEERING AND OUR END-TO-END BIOFABRICATION TECHNOLOGY

Cartilage

in cooperation with Charité
Lam et al.
Liver
functional liver
Lam et al.
Vasculature
in cooperation with Charité & JWI
Thomas et al.

Jawbone

in cooperation with Charité
Amler et al.

Amler et al.

Bone
in cooperation with BfR
in revision
Tumour
disease model for drug development
Grunewald et al.
Placenta
functional placenta barrier
Kreuder et al.