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TruDiagnosticModel SYMPHONYAge - Comprehensive Aging Analysis Tool

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SYMPHONYAge (System Methylation Proxy of Heterogeneous Organ Years) offers a novel approach to understanding aging by evaluating how different parts of the body age both independently and synchronously. By analyzing 11 distinct organ systems, SYMPHONYAge provides insights into the interconnected patterns of aging that influence various health outcomes. This method contrasts with other biological clocks that typically measure only nine systems, thereby offering a broader and more validated perspective on aging. Developed under the guidance of Dr. Morgan Levine, who specializes in aging mechanisms, the tool leverages the concept of epigenetics and DNA methylation. These epigenetic changes are critical in understanding why individuals with the same birth year may exhibit significantly different biological ages. The primary objective of SYMPHONYAge is not to eliminate aging or death but to delay the onset of age-related diseases and improve health span. By forecasting health outcomes through this comprehensive analysis, SYMPHONYAge aims to provide better healthcare insights and personalized health strategies.
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SYMPHONYAge (System Methylation Proxy of Heterogeneous Organ Years) is a new way of looking at aging by examining how different parts of the body age independently and synchronously.

This big-picture approach helps understand aging better by putting all the pieces of the puzzle together.

It’s crucial to note that our body’s systems don’t age in isolation. Many age-related illnesses stem from issues in various biological systems working together. For instance, arthritis is the result of both musculoskeletal wear and inflammation, whereas stroke can happen due to problems in the cardiovascular system, metabolism, inflammation, and brain function.

These interconnected patterns can lead to different aging types, making some people more prone to certain age-related diseases. Understanding these patterns helps in forecasting health outcomes.

 

SYMPHONYAge is notably different in scope, validation, and associations with various health outcomes by analyzing 11 different organ systems. Other biological clocks fall short in only measuring 9 differeny systems.

  • Brain
  • Immune System
  • Lungs
  • Blood
  • Inflammation
  • Metabolic
  • Heart
  • Kidneys
  • Musculoskeletal
  • Hormone
  • Liver