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EndoArt - Corneal Artificial Endothelial Layer
EndoArt corneal artificial endothelial layer, is the first synthetic implant to treat corneal edema, saving vision and restoring function by creating a new type of corneal availability. EndoArt® attaches to the back of the corneal surface, preventing the transfer of fluids into the cornea and inhibiting the buildup of fluid that we know as edema. Performed via small incisions, the procedure is minimally invasive, preventing further injury to fragile eye tissue and encouraging a high degree of implantation success.
EndoArt® has demonstrated a substantial decrease in edema, improvement in vision, and reduction in pain in clinical studies, and it is CE- approved as well as in Israel (AMAR).
The human ocular endothelium can never regenerate. Therefore, any damage to the endothelium, including aging, results in corneal edema: a swelling of the eye’s clear, dome-shaped outer surface. This affects millions of people around the world. Corneal edema causes pain and cloudy vision. If left untreated it can permanently damage the eye and affect sight. Current treatments for corneal edema depend on donated tissue. These transplants are often successful, but they are available only to those with access to human corneas. Meanwhile 13 million others experience first-hand the great shortage of donated corneas. They wait for human corneal transplants, in pain and with impaired vision, without an alternative solution.
EndoArt® creates a new type of corneal availability.
Made from synthetic materials, EndoArt® introduces an effective corneal edema treatment that is globally available and immediately ready to use.
EndoArt’s minimally invasive application is well tolerated because it is made of sterile biocompatible material that is inherent to human tissue and cannot be rejected.
EndoArt® can be manufactured in large quantities, plus future design development can even include refractive correction.
Mechanism of action
EndoArt® applies via a minimally invasive procedure.
It attaches to the posterior part of the cornea.
EndoArt® creates a passive barrier to fluids, allowing nutrition exchange on the periphery.
Fluid balance reverts to a normal level and the cornea clears