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Model Nevelia - Dermal Regeneration Template

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NEVELIA® dermal regeneration template is used to reconstruct the dermis following a skin loss. NEVELIA® dermal regeneration template is used to reconstruct the dermis following a skin lossNEVELIA® dermal regeneration template is a sterile medical device consisting of a collagen layer to promote dermal regeneration and a reinforced silicone layer acting as a pseudo-epidermis.

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The key features of NEVELIA® have been developed to achieve dermal reconstruction close to native skin thanks to:

  • Our expertise in the field of SKIN AND DERMAL REGENERATION
  • Our SCIENTIFIC APPROACH to development and manufacturing
  • Our know-how in COLLAGEN TRANSFORMATION

The bovine collagen type I, purified, stabilized, is supplied as a porous matrix. This dermal regeneration template serves as a support for cell infiltration and as a collagen matrix dressing, thus contributes to the natural tissue regeneration process. It is resorbed, becoming a vascularized tissue that is histologically very close to the normal dermis, from 2 to 3 weeks after it is implanted. The silicone layer is removed after dermal regeneration, at the time of the thin split thickness skin graft.

NEVELIA® is a three-dimensional porous matrix of stabilized bovine Collagen type I. NEVELIA® is made of a specific native collagen type I with a large fibrous proportion to keep cell adhesion signals and mechanical structure to support regeneration. In vitro tests demonstrate an optimized colonization as fibroblasts recognize collagen fibers.

Additional NEVELIA® features are:
• Optimized pore size (average pore size 100 μm) and open-cell structure promoting nutrients flow and fibroblasts migration
• Crosslinking rate for a balanced absorption / regeneration process
• No GAG added to keep cells attachment potential

NEVELIA® Bi-Layer Matrix is indicated for dermal regeneration in individuals with skin loss, particularly in the following fields:

  • Burns surgery (third and deep second degree burns)
  • Reconstructive plastic surgery
  • Traumatology

NEVELIA® dermal regeneration template is used in combination with a thin split thickness skin graft (STSG) to recreate skin resembling normal skin in terms of function and appearance.

  • Burns
  • Chronic wounds
  • Traumatology
  • Skyn tumors
  • Others

NEVELIA® can also be used in children.

NEVELIA®, AN ALTERNATIVE TO :

  • Skin Expansion (Single or sequential)
  • Flaps (Local, distant, free …)
  • Split-Thickness or Full-Thickness skin autograft
  • Dermal graft (Allografts, Xenografts…)