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Imedos - Dynamic Vessel Analysis
The aim of dynamic vascular analysis (DVA) is to examine the condition and function of the retinal vessels by measuring their diameter. We measure the vessel diameters because they are the actuators of autoregulation and reflect regulatory effects. With DVA, you can continuously measure these vessel diameters over time at a rate of 25 values per second and stimulate the microcirculation in any way you wish during this measurement. Stimuli such as light stimuli (flickering light), various respiratory gases, isometric exercises, etc. can be used. The examination is performed non-invasively and under real-time conditions and is completely painless. The standard application of the DVA is the investigation of the microvascular dysfunction (MVD), which plays a vital part in many microcirculation disorders as well as vascular diseases in various organs.- Vessel sections that need to be examined are marked in the image of the ocular fundus
- The DVA system determines the vessel diameters for these sections along the location and time
- All data is saved in a 3D database which can be analysed according to different questions
- Functional diagnostics: Using the video function, any stimulation, disturbance or event can be introduced to trigger and investigate specific vessel functions or reactions
As a special feature, the DVA system enables functional diagnostics which allows different autoregulative mechanisms to be stimulated or triggered separately during the recording of video sequences. By recording and evaluating these vascular responses, the mechanisms can be investigated and analysed accordingly.
Functional diagnostics, such as using flicker light as standard application, enables the examination of the vascular endothelial function and its nitric-oxide mechanism (flow induced autoregulation).
In addition to examining the large retinal vessels, the DVA system can also be used to study the behaviour of the capillaries as well as capillary regulation mechanisms, such as neurovascular coupling.
The system is not a medical device according to the Medical Device Regulation (MDR) and the Medical Device Law Implementation Act (MPDG), but is intended for research use.
The new DVA 3.0 can also be upgraded for research purposes using the following options:
- Digital video recorder for precise time recording of examination sequences and patient-related storage of video image sequences
- Free access to the design of measurement protocols
- ECG-wave interface for pulse recording and synchronisation (hardware and software module)
- Interface for recording of blood pressure (hardware and software module)
- Preparation of interfaces for further options
- Module for pulse analysis
The DVA 3.0, the third generation of our innovative DVA system, has been specifically developed for use in clinical routine. Featuring a compact and lightweight design, it offers the same optical imaging quality as the DVA+.
Features & Benefits:
- Painless, non-invasive examination
- High-precision optics and analysis features
- Standard examination protocol with flicker light
- 3 flicker cycles
- Image angle: 40°
- Technical measuring resolution < 1 µm
- Image resolution and resolution in vessel direction: 10 µm
- Time resolution: 40 ms
- Macula aperture
- Compact design for easy operation and maximum user flexibility
- Improved reproducibility of analysis results (internal fixation)