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UpcyteModel Hepatocytes - Expanded Primary Cells

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The liver is the main metabolic organ responsible for pathways such as glycolysis, glycogenesis, ureagenesis, as well as amino acid and lipid metabolism. The predominant cells type is the hepatocyte; therefore, cultured human hepatocytes are suited for in vitro metabolism studies. upcyte® Hepatocytes are expanded primary cells, derived from single donor primary cells. We can expand up to 2000 vials per hepatocyte donor from one vial starting material – data from different studies can now be compared while working with the same donor.

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  • metabolism (CYP induction & inhibition, transporters)
  • various toxicity formats
  • HCV infection and virus replication
  • various 3D formats & co-cultures
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  • different donors available
  • batch sizes up to 3000 vials per donor
  • primary cell morphology & polarity
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  • long term cultures for up to 4 weeks
  • characterized, standardized, cryopreserved, assay-ready
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