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ProxiCorModel CTR - Extracellular Matrix for Cardiac Tissue Repair

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An extracellular matrix derived from porcine small intestine submucosa (SIS), ProxiCor for Cardiac Tissue Repair (CTR) regulates the biologic healing response to decrease inflammation and stimulate formation of healthy tissue.2,3 When sutured next to healthy, viable tissue, ProxiCor is gradually replaced with native tissue as it remodels.

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In cases such as atrial or ventricular septal defect repair, ProxiCor can effectively repair a hole and generate new, healthy tissue in lieu of using synthetic patches or performing interventional procedures with devices such as nitinol plugs. Unlike synthetic alternative, SIS ECM has demonstrated a reduced foreign body reaction and post-op inflammation

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Our goal is to provide physicians a biologic reconstructive tool which also reduces post-operative complications and promotes long-term benefits. Accomplishing that goal is better for patient outcomes and satisfaction. ProxiCor is a natural biologic intended to remodel into healthy, site-specific tissue. Unlike synthetic options prone to inflammation and scarring, SIS ECM remodels into healthy tissue.5,6,7,8

  • ASD Repair
  • VSD Repair
  • Aortic Root Enlargement
  • Left Ventricular Aneurysm Repair
  • Sinus of Valsalva Aneurysm
  • Repair of Cardiac Tumors
  • Endocarditis
  • Use as a Pledget
  • Suture-Line Buttressing
  • Effectively repairs defects and restores natural cardiac tissue
  • Allows capillary in-growth and infiltration
  • Resists calcification
  • More resistant to infection than synthetic material