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Genovis GlyCLICK - Fluorophore Site-specific Conjugation Kit of IgG
FromGenovis Group
GlyCLICK is a site-specific conjugation technology for IgG using Fc glycan remodeling and click-chemistry. The technology generates stable and homogenous antibody conjugates for IgG from several species and subclasses. Fc-glycan remodeling by complete deglycosylation of the antibody allows for site-specific conjugation using robust click-chemistry, resulting in a degree of label (DOL) or drug-antibody ratio (DAR) of 2.
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GlyCLICK Fluorophore is available for site-specific labeling of 250 μg or 2 mg IgG with Alexa Fluor 488, 555 or 647, and is suitable for in vitro cell imaging, immunohistochemistry and flow cytometry.
- Site-specific fluorophore-conjugation to IgG with a degree of labeling (DOL) of 2
- Conjugation of IgG with preserved immunoreactivity
- Improved imaging quality in fluorescence microscopy applications