Sanesco Health

SanescoFull-Spectrum Methylation Formula

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MethylMax™ is a full-spectrum methylation formula for the support of all major methylation pathways.* Methylmax is commonly recommended for patients with an elevated norepinephrine/epinephrine ratio as well as for patients who exhibit decreased stamina and/or low energy.*

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Methylation plays a vital role in systems throughout the body including:  detoxification of heavy metals, regulation of gene expression, DNA repair, regulation of protein function, and synthesis/metabolism of some neurotransmitters. One of the important biochemical pathways methylation is intimately involved with is the homocysteine/methionine cycle. Homocysteine levels impact cardiovascular health.

MethylMax contains multiple ingredients that support methylation and a healthy homocysteine/methionine cycle.* B vitamins (B6, B9, and B12) help maintain healthy homocysteine metabolism.* Trimethylglycine (TMG) or betaine and SAMe are methyl donors in the homocysteine cycle.* In fact, TMG methylates homocysteine ultimately generating SAMe.*

SAMe is the primary methyl donor in the brain.* It is a required cofactor in the conversion of norepinephrine to epinephrine and serotonin to melatonin.* Additionally, SAMe is a cofactor for the enzyme catechol-o-methyltransferase, which breaks down catecholamine neurotransmitters.*

MethylMax may be recommended in conjunction with other TNT products such as Prolent™ and Procite-D™ to support healthy neurotransmitter levels. Given the importance of methylation, MethylMax may be recommended in Initial, Restoration, and Maintenance phases along the path to wellness.

Vitamin B6 (as pyridoxal-5’-phosphate) Active form of B6. Cofactor in the methylfolate cycle and metabolism of homocysteine.*

Folate (as (6S)-5-methyl-tetrahydro folic acid, glucosamine salt) (Quatrefolic®)?Active form of B9. Methyl group donor.* Cofactor in methylation reactions essential for the synthesis of dopamine, norepinephrine and epinephrine and break down of homocysteine.*

Vitamin B12 (as Methylcobalamin) Coenzyme form of Vitamin B12.* Methyl donor.* Supports homocysteine metabolism.*

SAMe (s-adenosyl-l-methionine)(as Adomix®) Activated form of a sulfur-containing essential amino acid. Primary methyl donor in the brain*6 Adomix is a room temperature stable form of SAMe.

Betaine (Trimethylglycine) Amino acid that functions as a methyl donor.* Supports SAMe production/recycling.*

Serving Size: 2 Capsules
Servings Per Container: 30

Methylation™ Formula  420.98 mg
Vitamin B6 (as pyridoxal-5-phosphate)
Folate (as (6S)-5-methyl-tetrahydro folic acid, glucosamine salt) (Quatrefolic®)
Vitamin B12 (as methylcobalamin)
Calcium (as dicalcium phosphate)
SAMe (s-adenosyl-l-methionine)(as Adomix®)
Betaine (Trimethylglycine)

Methylation is important for:

  • Detoxification of heavy metals
  • Regulation of gene expression
  • DNA repair
  • Regulation of protein function
  • Synthesis/metabolism of some neurotransmitters
  • Maintaining healthy homocysteine levels

SAMe plays roles in:

  • Phospholipid synthesis
  • Low mood
  • Connective tissue health
  • Healthy liver function
  • Attention