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DeltEx DRI CAR-T - Model INB-300 - Gamma-Delta T Cells
FromIN8Bio Inc.
INB-300, our DeltEx DRI CAR-T, is a preclinical product candidate combining our expertise in gamma-delta T cells, our DRI technology and a novel CAR-directed against the Cholotoxin peptide. Chlorotoxin binds to GBM tumor cells and has been previously utilized as a tumor paint in this setting. Chlorotoxin can also bind to other solid tumors including lung, breast and prostate cancers, among others.
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This video demonstrates the cytotoxicity of our DeltEx DRI CAR-T cells (clear) in vitro against glioblastoma cells that express green fluorescent protein (green). Our CAR-T cells work to efficiently swarm, attack, and eradicate the tumor cells and illustrate the direct killing action of these gamma-delta T cells.