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Pinnacle Technology
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Glucose Biosensor

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Pinnacle offers a GLUCOSE BIOSENSOR that is capable of providing real-time changes in glucose concentration in the brains of rodents. The glucose biosensor has outstanding performance characteristics and rejects all common electroactive interferents, including ascorbate. It has a linear range of at least 4 mM. We have successfully demonstrated that the glucose biosensor works in vivo and can provide continuous monitoring of brain glucose concentration changes for 96+ hours. This biosensor is warrantied for 21 days from time of shipment.

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Pinnacle`s glucose biosensor functions by the enzyme-mediated processing of the analyte of interest. This results in the production of hydrogen peroxide that is then detected by oxidation at a Pt-Ir electrode. Electroactive interferents present in the brain are excluded via a passive selective membrane and through active removal when necessary.

LINEAR SELECTIVE FAST

Pinnacle biosensors are selective for the analyte of interest and are linear at normal in vivo oxygenation levels over a physiologically relevant range, as shown in the diagrams below.

BIOSENSOR CALIBRATION

In order to relate the current changes measured by a biosensor to actual changes in analyte concentration, it is necessary to calibrate the biosensor at the conclusion of an experiment. The process also confirms the integrity and selectivity of the sensors. Pinnacle offers a number of in vitro calibration systems that allow the simultaneous calibration of four to eight biosensors. Select the calibration kit that matches the hardware system and cannula type used in your experimental setup.