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Bag - Model HISTO TYPE SSP / KIR TYPE SSP - HLA and KIR Typing Kit
Fast HLA typing for smaller sample volumes and confirmatory tests? Look forward to extremely simple handling with HISTO TYPE SSP Kits. It is considered a robust and well established solution for low-resolution typing based on sequence-specific primers.
- Reliable: Robust against fluctuations in DNA concentration.
- Convenient: user-friendly HISTO MATCH software for evaluation and documentation for all loci
- Easy to implement: only basic PCR laboratory equipment needed (thermocyler and gel electrophoresis)
Thanks to the CE -certified and validated Taq polymerase, HISTO TYPE SSP sets quality standards.
The KIR TYPE SSP Kit allows genotyping of 14 Killer cell Immunoglobulin-like Receptor (KIR) genes plus 2 pseudogenes. It gives additional information on possible disparities between KIR and the respective HLA ligands in the context of transplantation.HISTO TYPE SSP - IN DISEASE ASSOCIATIONS AND PHARMACOGENOMICS
Benefit from our simple SSP solutions for specific clinical applications related to HLA alleles.
Coeliac disease
Coeliac disease is strongly associated with the DQA1*05:01- DQB1*02:01 and DQA1*03-DQB1*03:02 haplotype. Additionally, DRB1*03, DRB1*07 and DRB1*11 alleles can be used as genetic markers.
Morbus Bechterew et al.
Seronegative arthritic diseases like Morbus Bechterew, Morbus Reiter and post infectious reactive arthritis are strongly associated with HLA B*27. Determination of the presence of HLA B*27 is a valuable tool in the diagnosis of these diseases.
Narcolepsy
98 % of the Caucasian narcolepsy patients carry the DRB1*15:01- DQA1*01:02-DQB1*06:02 haplotype.
Abacavir hypersensitivity
Some patients develop a hypersensitivity reaction against the antire- troviral drug abacavir which is used e.g. for HIV therapy. This hypersensitivity is associated with the allele HLA B*57:01
KIR TYPE
KIR typing is used as complimentary diagnostic before bone marrow transplantations and for immunogenetic studies. The KIR TYPE kit enables genotyping of 14 KIR genes and 2 pseudogenes.
- cost effective because of kit format with Happy Taq Polymerase included
- reliable results - Happy Taq Polymerase is CE certified and validated
- free user-friendly HISTO MATCH software for evaluation and documentation
- easy to implement because only basic PCR lab equipment is needed