SimpliDerm - Hydrated Acellular Dermal Matrix
The natural allograft option that is as close to nature as possible. SimpliDerm® is a pre-hydrated human acellular dermal matrix with a sterility assurance level (SAL) of 10-6 and requires a minimal 2-minute sterile rinse for convenient intraoperative use.1 By maintaining a more intact matrix, SimpliDerm enhances and supports the angiogenic process, provides a more pliable matrix, and results in a lower risk of inflammatory response3, fast integration and rapid revascularization.4 SimpliDerm is available in both Ellipse™ and rectangular sizes designed to meet a range of surgical needs and provide intraoperative ease of use1,2. SimpliDerm with perforations is available to facilitate plane-to-plane fluid transfer upon implantation.2
- Innovative processing
- Lower inflammatory response
- Rapid integration
- Pliable matrix
- A lower inflammatory response at 4 weeks
- A significantly lower pro-inflammatory M1 macrophage protein (TNFα) response (p
- Lower fibrotic response at 12 weeks
- Greater tissue strength and suture retention at 12 weeks
Aziyo uses a proprietary, patented and gentle process to achieve a sterility assurance level (SAL) of 10-6, while preserving the key growth factors of native dermis. Due to this unique proprietary process, SimpliDerm offers a more pliable, intact matrix membrane that supports the angiogenic process, demonstrating a lower risk of inflammatory response3, faster integration and more rapid revascularization.