Enterome - Model EB1010 - IBD, Food Allergy

EB1010 is an orally administered, GI-selective next generation IL-10 inducer designed to induce high local secretion of IL-10 for the treatment of Inflammatory Bowel Disease (IBD) and food allergy. EB1010 is a peptide that modulates the immune system by closely mimicking effects of a specific class of hormones. IL-10 deficiency is central to auto-immune, inflammatory and allergic diseases and a major opportunity exists for an IL-10 inducer that can overcome the limitations of earlier recombinant IL-10 candidates, such as poor stability and tolerability and high systemic dose with limited local exposure. EB1010 is due to enter the clinic in 2023.