MHC I Dextramer - Model CD8+ T Cells - Identify Antigen-Specific Flow Cytometry

Antigen-specific CD8+ T cells play an important role in the immune response of autoimmune disease, cancer, transplantation, infectious disease, and allergy. MHC I Dextramer® reagents can identify antigen-specific CD8+ T cell subsets by flow cytometry. MHC I Dextramer reagents consist of a protein-stabilizing dextran backbone, an optimized number of MHC-peptide complexes, and fluorophores (PE, APC, or FITC) no fluorophore (None). Immudex manufactures MHC I Dextramer reagents as listed in the table below. Customized reagents are easily made with MHC alleles from our catalog and with peptides that form stable complexes with the MHC molecule.