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MHC II Dextramer - Model CD4+ T Cells - Identify Antigen-Specific Flow Cytometry
Antigen-specific CD4+ T cells play an important role in the immune response of autoimmune disease, cancer, transplantation, infectious disease, and allergy. MHC II Dextramer® reagents can identify antigen-specific CD4+ T-cell subsets by flow cytometry. MHC II Dextramer reagents consist of a protein-stabilizing dextran backbone, an optimized number of MHC-peptide complexes, and fluorophores (PE, APC or FITC) or no fluorophore (None). Immudex manufactures MHC II Dextramer reagents as listed in the table below. Customized reagents are easily made with MHC alleles from our catalog and with peptides that form stable complexes with the MHC molecule.
Push the boundaries of your flow cytometry assays with MHC II Dextramer® reagents. Designed for high avidity and exceptional signal-to-noise ratio, MHC II Dextramer® reagents enable you to detect antigen-specific CD4+ T cells with confidence.
- Get the full picture of CD4+ T-cell responses, even the low-affinity ones.
- Ensure consistent, reproducible, and comparable results.
- Expand the limits of your research.
- Secure flexibility in your experiments.
You can order MHC II Dextramer® reagents in one of three ways:
- Use the table below to find and order your MHC II Dextramer® reagent
- If you can’t find the reagent to meet your research needs, create a custom reagent
- Alternatively, send an e-mail to ordering@immudex.com specifying:
- Catalog number or desired MHC allele-peptide combination.
- Consult our lists of available MHC alleles
- Calculate the predicted MHC-peptide affinity using our prediction tool - Fluorophore (PE, APC, FITC, or none)
- Test size (50,150, 500, 1000 tests). One test is 10 µl reagent and sufficient to stain 1–3 x 10^6 lymphoid cells or 1–3 x 10^5 clonal antigen-specific T cells.
Immudex has updated the catalog numbers. To learn more about it, please consult the document here