Optical Q - Immunoassay For the Quantitative Determination of AFP
Alpha-fetoprotein (AFP) is a major plasma protein produced primarily in the liver of a developing fetus. It can be found in maternal blood and in amniotic fluid since it is secreted into fetal serum. A great increase of AFP concentration in several malignant diseases mostly is primary hepatocellular carcinoma and non-seminoma testicular cancer.
High concentration of AFP is also found in patients diagnosed with gastrointestinal tract cancer, viral hepatitis, chronic active hepatitis, alcoholic cirrhosis, adenocarcinomas of lung, pancreas, and gall bladder. Since AFP is well known to be an important prognostic indicator of non-seminoma testicular cancer, its most definitive role is on monitoring post-treatment clinical status and the post therapeutic evaluation of patients.
- Working range: 1.0-400.0 ng/mL
- Reference range: <15 ng/mL
- CV: <10%
- Sample type: Serum / Plasma
- Sample volume: 100 µL
- Loading volume: 100 µL
- Assay time: 15 minutes
- Storage condition: Cartridge: 2-30 °C / Detection buffer: 2-8 °C
- Shelf life: 24 months