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InnoSer Belgie NV
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  5. InnoSer - Model P10 - In Vivo ADPKD ...

InnoSer - Model P10 - In Vivo ADPKD Mouse Model for Polycystic Kidney Disease

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Quick progression of cyst formation in the distal segment of the nephron

Most popular related searches
polycystic kidney disease
in vivo model
kidney disease
blood sampling
kidney injury
disease progression
histopathology
nephrology
  • Body weight (monitored daily)
  • Kidney weight
  • Kidney weight to body weight ratio
  • Urea measurement
  • Histopathology: cystic index and pathological lesions
  • Ultrasound imaging to determine kidney volume

  • Multiple well established models
  • AAALAC accredited facilities
  • Organ and blood sampling for additional tailored analysis

InnoSer offers different ADPKD mouse models by specifically timed Tamoxifen-induced Pkd1 knockout. There are three models available depending on which post-natal (P) day Tamoxifen is administered: 

The P10 model is widely used as a first screening platform as it offers quick and robust results with renal cyst formation, while the P18 and P40 models show a slower progression even closer to clinical phenotypes. 

For all your nephrology projects, we support custom in vivo models for kidney injury and toxicological studies.