InnoSer Belgie NV
InnoSer - Model P40 - In Vivo ADPKD Mouse Model for Polycystic Kidney Disease for Polycystic Kidney Disease
Slow and reproducible cyst formation in the proximal part of the nephron
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- Multiple well established models
- AAALAC accredited facilities
- Organ and blood sampling for additional tailored analysis
InnoSer offers different ADPKD mouse models by specifically timed Tamoxifen-induced Pkd1 knockout. There are three models available depending on which post-natal (P) day Tamoxifen is administered:
The P10 model is widely used as a first screening platform as it offers quick and robust results with renal cyst formation, while the P18 and P40 models show a slower progression even closer to clinical phenotypes.
For all your nephrology projects, we support custom in vivo models for kidney injury and toxicological studies.