Chenghou - Iron Dextran Injection Brown to Brown Black Crystalline Powder
ANTIANEMIA drug. Iron is an important component of hemoglobin, Myoglobin, and various enzymes (Cytochrome C oxidase, succinate dehydrogenase, Xanthine oxidase, etc.) . Iron deficiency can not only cause anemia, but may also affect other physiological functions. Normal dietary intake is usually sufficient to maintain iron balance in the body, but iron requirements increase during lactation, pregnancy, and certain iron deficiency anemia conditions, iron supplementation can correct abnormal physiological symptoms and decrease of hemoglobin level caused by iron deficiency.
Pharmacological action
Dextran iron is absorbed slowly by the lymphatic system after injection. About 60% of the iron is absorbed within 3 days of injection and 90% within 1-3 weeks. The remaining drugs may be absorbed slowly within a few months. Reticuloendothelial cells from the liver, spleen, and bone marrow gradually remove absorbed drugs from the plasma. Iron dissociated from Dextran immediately binds to the protein molecules to form Hemosiderin, Ferritin, or Transferrin. And Dextran are metabolized or excreted.