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Sumitomo Tumor Growth Equipment & Supplies

3 equipment items found

Sumitomo - Model DSP-0390 - Emopamil-Binding Protein (EBP) Inhibitor

Sumitomo - Model DSP-0390 - Emopamil-Binding Protein (EBP) Inhibitor

by:Sumitomo Pharma Oncology, Inc.   based inCambridge, MASSACHUSETTS (USA)
EBP is an endoplasmic reticulum membrane protein involved in cholesterol biosynthesis.47 When functional, EBP mediates de novo cholesterol synthesis for cell membrane structure and signaling, enabling aberrant growth of tumors.47-50 Inhibition of EBP causes an accumulation of its substrates zymostenol and zymosterol, which contributes to lethal autophagy in ...
CONTACT SUPPLIER

Sumitomo - Model TP-3654 - Investigational Oral PIM Inhibitor

Sumitomo - Model TP-3654 - Investigational Oral PIM Inhibitor

by:Sumitomo Pharma Oncology, Inc.   based inCambridge, MASSACHUSETTS (USA)
TP-3654 is an oral investigational inhibitor of PIM kinases, which has potential antitumor and anti-fibrotic effects through multiple pathways, including induction of ...
CONTACT SUPPLIER

Sumitomo - Model TP-1454 - Investigational Oral Pyruvate Kinase M2 Isoform (PKM2) Activator

Sumitomo - Model TP-1454 - Investigational Oral Pyruvate Kinase M2 Isoform (PKM2) Activator

by:Sumitomo Pharma Oncology, Inc.   based inCambridge, MASSACHUSETTS (USA)
TP-1454 is an investigational oral pyruvate kinase M2 isoform (PKM2) activator.44 This activation is thought to starve cancer cells of important molecular building blocks, inhibiting tumor cell proliferation, and enhancing antitumor ...
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