Stanford Chemicals - Medical Grade Sodium Hyaluronate

• ophthalmic surgery (viscosupplementation)
• intra-articular injections
• intradermal injections for aesthetic correction
• anti-adhesive wound healing products
• eye drops for dry eye (eg. artificial tears)
• topical preparations for wound and burns healing
• anti-adhesive and shape keeping products for thoracic and abdominal surgery
• bandages with exudates absorbing capacity

2. Remedies /Drugs:

• Sodium hyaluronate on its own as active substance
• cartilage (joint) and tendon disorders wound and burns healing preparations
• Sodium hyaluronate in combination with other active substances
• anti-cancer preparations
• wound and burns healing preparations
• preparations for reduction of scar formation
• eye drops
• topical anti-inflammatory and analgesics preparations
• cartilage (joint) and tendon disorders
• nutraceuticals supporting the treatment  of skeleton or prevention of skeleton disorders
• preparations for liver regeneration

3. Issue Engineering

• artificial skin grafts for plastic and reconstruction surgery
• artificial skin for the test of cosmetic raw material
• replacement of injured cartilage, artificial cartilage grafts
• artificial bone grafts
• adipose tissue replacement
• support for the growth of soft tissue grafts
• aorta and large venous grafts industry

4. Application in Biotechnology and Molecular Biology

• component of special cell culture medium
• supporting material for gene transfer
• biotinylated for detection of hyaluronan binding proteins

5. Other Biological Applications

• sperm separation according to their mobility
• medium for in vitro ovum fertilization. For parenteral preparations or oral preparations not including intra-articular and intra-ocular preparations. It can be used in eye drops, contact lens solutions, topical preparations for the wound or burn healing, medical lubricants, etc.

Items/Specifications

• Appearance: White powder
• Infrared absorption spectrophotometry: Ph. Eur. Reference Standards
• Appearance of solution: A600nm≤0.01
• pH (5mg/mL solution): 5.0-8.0
• Intrinsic viscosity: Measured values
• Molecular weight: Measured values
• Sulfated glycosaminoglycans: ≤1%
• Nucleic acid: A260nm≤0.5
• Protein: ≤0.1%
• Chlorides: ≤0.5%
• Iron: ≤80ppm
• Heavy metals: ≤20ppm
• Loss on drying: ≤20.0%
• Bacterial counts: ≤100cfu/g
• Mold and Yeast: ≤100cfu/g
• Sodium hyaluronate: 95%-105%
• Glucuronic acid: ≥42.0%

• Viscoelasticity, protecting corneal endothelium;
• Lubricating, viscoelasticity, repairing damage cartilage, inhibition of inflammation, pain relief, etc.;
• Properties of good biocompatibility and degradability of HA and its derivatives.