Peel & Stick - Microneedle Patch
Micron’s “peel & stick” microneedle patch is applied simply by pressing it against the skin, like a BAND-AID®. This simple and minimally-invasive approach eliminates pain and fear associated with injections and allows for self-administration with little to no training.
Targets Skin
Upon application of the patch to the skin, microneedles painlessly penetrate the upper layers of skin and dissolve rapidly, thereby releasing their drug(s) or vaccine(s). After a few minutes, the patch is removed from the skin. Because the microneedles dissolve in the skin, there is no sharps waste.
Improves Efficacy
By delivering medicines into the outer layers of skin, the microneedle patch targets dermal immune system cells, which has been shown to elicit enhanced immune responses and dose sparing when vaccines are delivered by microneedle patch. Also, the microneedle patch targets blood capillaries just below the epidermis, which has been shown to enhance the pharmacokinetic and pharmacodynamics effects of certain drugs.
Painless
Because the microneedles penetrate only the upper layers of skin, they do not reach the deeper nerve endings, which makes Micron’s microneedle patch painless.
Thermostable
Micron’s proprietary formulation and manufacturing processes have been shown to provide thermostability to encapsulated drugs and other actives, thereby allowing for reduction and sometimes elimination of the cold chain.
Versatile
Microneedle patches are suitable for a wide range of active (therapeutics and vaccines) and inactive compounds including small molecule, nucleic acids, peptides, proteins, and micro/nano-particles.
Micron has assembled a team of scientists and engineers with medical device, biopharmaceutical, analytical, quality, and cGMP manufacturing experience who work in state-of-the art facilities that include wet laboratory and cleanroom space. Micron works with a network of consultants and CROs to define and execute regulatory strategies, including preclinical and clinical studies.
Micron’s capabilities include:
- Formulation, process, and product development
- Microneedle patch and packaging design, prototyping, testing
- Analytical methods
- Pre-clinical testing
- cGMP manufacturing of clinical trial materials
- Preclinical and clinical study design support
- Regulatory strategy and filing