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EKU - Model NO-A - Nitric Oxide Delivery System
In June 2010 EKU Elektronik received the outpout orientated innovation award "Success" by the Investitions- und Strukturbank Rheinland-Pfalz (ISB) GmbH for the successful development of the NO-application device NO-A. EKU Elektronik received the award for the NO-A, a therapy device for the application of nitric oxide (NO) therapy gas in the ventilation flow of an intensive care patient in connection with different ventilators. The inhaled nitric oxide (iNO) therapy shall reduce the clinical necessity of a left-to-right shunt and contribute to cardiac relief. In order to improve the oxygenation of ventilated patients nitric oxide (NO) is added to the respiratory gas.
It is applied for the treatment of newborns, children and adults with pulmonary hypertension, oxygen deficiency, neonatal pulmonary failure, persistent pulmonary hypertension of neonates, pulmonary fibrosis, chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ARDS). Furthermore the device is used in cardiac surgery (cardiac valve diseases and cardiac transplantation) to treat an increased pulmonary pressure, as inhaled NO has a dilating effect on the blood vessels in the lung and therefore significantly improves the haemodynamics of the patient. Please refer to the relevant details listed in the information accompanying the finished medicinal product.?
- neonatal, paediatric or adult application
- direct connection by ventilator interface
- optional flow sensor for support of external ventilators of different brands
- convenient design and comprehensive power supply for intrahospital transport (mains, 12V, battery)
- dual cylinder management: operation with one or two cylinders with automatic flush and cylinder switching
- wide-ranging cylinder compatibility (50 – 1000 ppm)
- fail-safe dosing by secondary dosing system
- wide dosing range by clocked dosing (13 µl/min – 17 l/min)
- extended concentration range (0.1 – 99.9 ppm)
- triggered or continuous dosing mode
- dosing trend (1 h / 24 h)
- timer (for non-responder-test or weaning)
- integrated gas monitoring
- optional oxygen monitoring
- ambient air monitoring
- interface connection to PDMS (e.g. via Philips VueLink/IntelliVue, EKU-PDMS and others)
The NO-A has different operating and dosing modes which enable a combination with almost any ventilator. Besides the manual operation, which enables the user to adapt the therapy to a wide spectrum of ventilation situations by adjusting the ventilation flow independently, the NO-A offers two other operating modes which automatically adjust to the conditions in the ventilation circuit with the ventilator interface and a flow sensor.
The dosing modes differ from continuous and triggered dosing mode. An optional third mode even allows the operation in semi-closed systems of anaesthesia units by a dosimetric procedure (currently only available in Germany).
via ventilator coupling
EKU Elektronik is the only manufacturer of nitric oxide delivery systems with electronic connection (interface) to different ventilators of well-known manufacturers. By the connection to the ventilator the required volume is automatically dosed close to the patient corresponding to the adjusted target concentration.
This direct coupling to the ventilator enables:
- economy in consumption of the therapy gas
- continuous adjustment to a wide-ranged therapeutic application frame
- automatic adjustment for therapeutic maneuvers
- short NO standing times in the breathing gas and consequently minimization of risks caused by conversion products