- Home
- Companies
- Yourgene Health
- Products
- IONA - Model Nx - Non-Invasive Prenatal ...
IONA - Model Nx - Non-Invasive Prenatal Test Kit for Clinical Laboratories
The IONA Nx NIPT Workflow (IONA Nx) is Yourgene Health’s non-invasive prenatal test (NIPT) that runs on the Illumina NGS platform. A fully validated workflow that utilises next generation sequencing (NGS) and has been developed to run on Illumina’s NextSeq 550Dx instrument.
Key Features of the IONA® Nx NIPT Workflow
- Advanced proprietary reagents and software technologies
- Simple process with minimum instrumentation capital expenditure, suppliers and contract services
- Designed to offer flexibility (automated or manual) and scalability to suit varying customer needs
IONA® Nx, is a screening test that performs:
- Whole genome analysis to measure the likelihood that a pregnant woman is carrying a fetus with:
Most common trisomies
- Trisomy 21 (Down’ Syndrome)
- Trisomy 18 (Edwards’ Syndrome)
- Trisomy 13 (Patau’s Syndrome)
Autosomal Aneuploidies (AAs)
- Additional trisomy across the whole-genome
- All monosomy across the whole-genome
Sex Chromosome Aneuploidies (SCAs)
- 45,X (Turner Syndrome)
- 47,XXX (Trisomy X)
- 47,XXY (Klinefelter’s Syndrome)
- 47,XYY (Jacob’s Syndrome)
- Fetal Sex Determination
The IONA Nx NIPT Workflow is a fully validated workflow which utilises Next Generation Sequencing technology, to estimate the risk of a fetus having Trisomy 21, Trisomy 18, Trisomy 13, Autosomal Aneuploidies (AA), Sex Chromosome Aneuploidies (SCA) and the most clinically relevant microdeletions.
The IONA® Nx NIPT Workflow is suitable for use from 10 gestational weeks for singleton or twin pregnancies. The workflow can deliver results from 2 to 3 days.