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Model ARP43128_P050 - Polyclonal FBXO7 Antibody - Middle Region

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25 ugof the indicated Human whole cell extracts was loaded onto a 12%SDS-PAGEgel. 3 ug/mL of the antibody was used in this experiment.

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  • Tested Species Reactivity : Human
  • Predicted Species Reactivity : Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish
  • Product Format : Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  • Clonality : Polyclonal
  • Host : Rabbit
  • Application : IP, WB
  • Reconstitution and Storage : For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
  • Immunogen : The immunogen is a synthetic peptide directed towards the middle region of human FBXO7
  • Purification : Affinity Purified
  • Predicted Homology Based on Immunogen Sequence : Cow: 100%; Dog: 100%; Guinea Pig: 83%; Horse: 92%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 100%; Rat: 93%; Zebrafish: 83%
  • Complete computational species homology data : Anti-FBXO7 (ARP43128_P050)
  • Peptide Sequence : Synthetic peptide located within the following region: PGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDG
  • Concentration : 0.5 mg/ml
  • Blocking Peptide : For anti-FBXO7 (ARP43128_P050) antibody is Catalog # AAP43128 (Previous Catalog # AAPP25101)
  • Sample Type Confirmation :
  • FBXO7 is supported by BioGPS gene expression data to be expressed in MCF7
  • Other Applications Image 1 Data : Immunoprecipitation -- 5ug antibody
  • Reference : Chang,Y.F., (2006) Biochem. Biophys. Res. Commun. 342 (4), 1022-1026
  • Publications :
  • Chemical inhibition of FBXO7 reduces inflammation and confers neuroprotection by stabilizing the mitochondrial kinase PINK1. JCI Insight. 5, (2020). 32493843
  • The Parkinson`s disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy. Nat Neurosci. 16, 1257-65 (2013). 23933751