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GS-International - Model CAS -59-46-1 - Procaine
CAS No.: 59-46-1 (free base) . Molecular Formula: C13H20N2O2(free base). Molecular Weight: 236.31 g/mol (free base) / 272.77 g/mol (HCl). Appearance: White crystalline powder (free base); colorless crystals or white powder (HCl). Melting Point: 61°C (free base); 153–156°C (HCl). Boiling Point: 373.6°C (free base, at 760 mmHg). Density: 1.1 g/cm³ (free base). Refractive Index: 1.543.
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Safety and Handling
- GHS Hazard Codes: H315 (Skin irritation), H319 (Eye irritation), H335 (Respiratory irritation)
- Precautions: Use PPE (gloves, goggles), avoid inhalation, and work in a fume hood.
- First Aid: Rinse eyes/skin with water; seek medical attention for ingestion or severe exposure
- Category: Description
- Medical Uses:
- Local anesthesia: Infiltration, spinal, nerve block, and surface anesthesia (mucous membranes)
- Diagnostic/therapeutic nerve blocks
- Dental procedures
- Metabolism: Hydrolyzed by plasma pseudocholinesterase into para-aminobenzoic acid (PABA) and diethylaminoethanol; renal excretion
- Industrial Applications: - Intermediate in synthesizing dyes and agrochemicals
- Research reagent in biochemical assays (e.g., cholinesterase activity tests)