OPKO Rayaldee - Model calcifediol - Prohormone of the Active Form of Vitamin D3

Rayaldee® (calcifediol) is an extended-release prohormone of the active form of vitamin D3 that both raises 25-hydroxyvitamin D and lowers intact parathyroid hormone (iPTH) levels in patients with stage 3 or 4 CKD. Rayaldee® is under development for adult patients with stage 5 chronic kidney disease (CKD) with SHPT and vitamin D insufficiency who require regular dialysis.