Engine - Model hEXselect - Protein Array

The hEXselect protein expression library was derived from the hEX1 library by in silico analysis and re-arraying. Genes which were available in a high clone number were reduced to decrease redundancy. Expressed proteins, which were available only as a single copy were doubled for successive production of high density protein Arrays. The hEXselect protein expression library contains 23.806 clones. Like the hEX1-library, it comprises full-length as well as shorter cDNA clones. All clones have been 5’ tag sequenced and are fully annotated. The size of the low redundancy collection allows a complete spotting in duplicates onto a single Protein Array, which saves processing time and hybridisation probe volume. The majority of the clones represent partial proteins, which may include artificial protein sequences corresponding to the 5’UTR sequences, with one third matching to the human proteome.