Advanced Oxygen Therapy Inc.
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AOTIModel TWO2 - Single Use Topical Wound Oxygen Therapy Controller

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AOTI offers single use Topical Wound Oxygen (TWO2) therapy products to allow therapy to be applied effortlessly to patients suffering with wounds at home and across a range of healthcare facilities. TWO2 therapy allows for targeted treatment utilizing cyclical pressurized oxygen applied directly to the wound site. TWO2 therapy delivers the highest Topical Oxygen Therapy (TOT) diffusion pressure gradient available, allowing for more durable healing of previously chronic non-healing and acute complex wounds, providing significant clinical, and quality of life and cost saving benefits.

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TWO2 therapy is indicated for any type of acute or chronic wound, including: Diabetic Foot Ulcers (DFU), Venous Leg Ulcers (VLU), pressure ulcers, dehiscences, post surgical and burn wounds. Wounds that are both infected and/or ischemic can be successfully treated with TWO2 therapy, as the therapy helps to correct local tissue hypoxia, as well as the underlying problems caused by peripheral vascular disease, while maintaining an ideal moist wound healing environment.

When applying TWO2 therapy, there is no need to remove gas permeable dressings or compression bandages, making it convenient to use. The TWO2 therapy extremity system is comprised of three major components: A single use Extremity Chamber, Controller and oxygen source. An oxygen flow rate of 10 lpm is used to cycle the therapy pressure between 10 and 50 mb directly at the wound site, within a sealed and humidified environment, providing an oxygen partial pressure diffusion gradient of close to 800 mmHg. This allows for the maximum penetration of oxygen into the wounded tissue. Simple on-screen step-by-step instructions provide easy direction for patients and caregivers to apply the therapy at home.