Merck KGaA, Darmstadt, Germany
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Model 53218-U - SupelMIP Beta blockers (class selective) 25 mg / 10 mL

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A class selective MIP phase for the multi-residue extraction of beta-blockers in water and biological fluids. SupelMIP - Beta-blockers was developed for the selective extaction of a broad range of beta-blockers such as altenolol, betaxolol, carazolol,metroprolol, pindolol, propanolol, sotalol and timolol, and others. The SupelMIP cartridge offers excellent reproducibility for surveillance of this common class of drugs of abuse. Loading capacity is superior to immuno-affinity columns, and MS-detection is recommended for forensic validity. Detailed extraction protocols are included with the product. The methods are highly reproducible and offer beta-blocker recoveries of > 80%. The method minimizes matrix effects and offers limits of detection of less than 5 ppt in water and less than 10 ppt for plasma and urine. SupelMIP is a registered trademark of Sigma-Aldrich Co. LLC
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