Origin, Inc

IonositeSurgical Site Infection Clinical Pipeline

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SSIs represent a significant burden in terms of patient morbidity and mortality, and add significant costs to health systems and service payers worldwide (49). CDC has reported costs of $5 billion, but estimates elsewhere in the literature have reached as high as $29 billion per year (48).

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IonoSite™ has promise as a means to help reduce the risk of - or treat - SSI. Evidence includes:

  • Nitric Oxide’s antimicrobial properties (4-8)

  • Evidence suggesting that Origin’s technology can facilitate NO-penetration into tissue (47)

  • Evidence from the “Plason’’ plasma device (a precursor device based on core IonoJet™ technology). The Plason has been used to treat more than 10,000 patients with a wide variety of skin wounds and other disorders The patient group included individuals with complicated, protracted post-operative wounds. The treatment markedly accelerated the healing process throughout this group. (50)