Parametrics - Synthetic Bone Void Fillers
Synthetic bone void fillers are safe, biocompatible, and easy to use. These resorbable biomaterials are based on nano-crystalline hydroxyapatite (HA) and purified collagen technologies. These products are engineered to optimize the resorption rate. Our granules are composed of 60% HA and 40% β-Tricalcium Phosphate (TCP). The formulation provides optimal osteoconduction, and the composition mimics that of human cancellous bone. Our strips are a combination of granules embedded in a fibrillar bovine collagen matrix. Once rehydrated, the foam is flexible. Our bioactive glass foam strips are sterile bone grafts composed of highly purified fibrillar Type I bovine collagen, bioactive glass granules, and HA/TCP granules. It functions as an osteogenic stimulus to which the patient’s bone marrow can be added before implantation.
Bone grafting is a surgical procedure that replaces missing bone and provides a scaffold for new bone growth. Bone grafts may be autograft (obtained from the patient’s body), allograft (obtained from a donor), or synthetic.
Benefits of using allograft/synthetic versus autograft include:
- Eliminates the need for a second surgical site
- Reduced pain and loss of function from the second surgical site
- Reduced surgical time
- Reduced risk of infection or bleeding
- Reduced recovery time after surgery
Successful bone grafts have one or more of these three properties:
- Osteoconductive: graft acts as a scaffold for the growth of natural bone
- Osteoinductive: graft contains growth factors that recruit immature cells and stimulate those cells to develop into active bone-forming cells called osteoblasts
- Osteogenic: graft directly provides living cells that contribute to the growth of natural bone