Celemics - Model BRCA 1,2 - Target Enrichment Panel

Using Celemics‘ BRCA 1,2 Panel customers can obtain information on all types of variants including large indel and CNV. High performance of the panel guarantees reliable and consistent sequencing results to customers even if using DNA from low-quality clinical samples or FFPE. Additionally, Celemics provides clinical-grade reports from our proprietary bioinformatics pipeline and in conjunction with Strand Life Sciences.

Targets the whole CDS (+/- 40) and promoter regions of BRCA 1,2 with high specificity

• Target regions not only cover CDS regions, but are expanded by ±40 of CDS to detect splicing site variants.
• Probes specifically designed for detecting deletion, duplication, and large rearrangement

Compatible with a variety of sample types

• No compromise on panel performance regardless of specimen types, even for challenging ones such as blood or FFPE

Market leading panel performance in uniformity and coverage

• Designed to target the whole exon regions of BRCA 1, 2 gene with 100% coverage (RefSeq) and validated to yield 100% coverage

Clinical grade performance

• CE-IVD certified target enrichment panel
• Greater than 95% sensitivity and 99.5% specificity for all types of mutations (SNV and Indel)

Provision of Bioinformatics SW

• FASTQ to annotated VCF
• Clinical grade report
• EU-GDPR compliant through usage of Europe-based server