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CD BioSciencesVirus-Like Particles (VLP) Plant

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VLPlant can synthesize expression vectors according to target genes provided by customers, and of course we can screen target genes for you. The vector containing the gene of interest is transformed into plant cells infiltrated in a transient expression system (mediated byAgrobacterium) to produce VLPs. Once plant growth is complete, we harvest the plant cells, isolate and purify the VLPs, and test them for biochemical, biophysical and biological characterization.

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As the world`s leading custom service provider,CD BioScienceshas advanced equipment and experienced scientists dedicated to providing clients with the highest quality comprehensive solutions. We provide you with a variety of services for the construction of virus-like particles (VLPs) from plant platforms, including production, purification, modification and characterization assays to aid in the development of your vaccines, drug delivery systems and diagnostics for viral infections.

VLPs are nanoscale structures composed of assembled viral proteins that lack viral genetic material and are not infectious. Plant-based recombinant expression systems have many advantages over traditional bacterial, yeast, insect, and mammalian expression systems, such as no fermentation-related systems and expensive cell culture facilities and can be produced on a large scale. In addition, the plant expression system has a low risk of introduction of foreign human pathogens, as well as a low risk of contamination with bacterial endotoxins. Therefore, plant-based recombinant expression systems are promising platforms.

Vaccine Development

VLPs built on plant-based platforms can help you develop a variety of vaccines against viruses or bacteria for disease prevention.

Drug Delivery System

VLPs are delivery platforms with nanoscale structures that can deliver drugs, proteins/peptides, nucleic acids, and other substances for disease treatment.

Viral Infection Diagnosis

VLPs can be developed as a positive control for virus detection and can also be used as a coating antigen to develop ELISA for virus infection diagnosis.