MtoZ Biolabs - Model active-pharmaceutical-ingredients-identification - Active Pharmaceutical Ingredients (APIs) Identification Service

Active Pharmaceutical Ingredients (APIs) are substances or mixtures employed in the production of drugs. They have pharmacological effects or directly contribute to diagnosing, treating, mitigating symptoms, controlling, or preventing diseases, in addition to influencing the structure or function of the body. The identification of APIs is critical in drug development. Elucidating the structures and properties of APIs is pivotal for guiding subsequent studies of their physicochemical properties, structural modifications and screenings for their pharmacological efficacy, which potentiate their development of novel drugs.

The primary sources of APIs include:

1. Extraction from natural medicines.

2. Derivation. It can be obtained through structural modification or found in metabolites from existing medications.

3. Discovery via pharmacological model screenings. Employing extensive libraries of compounds in conjunction with high-throughput screening techniques can find components with medicinal potential and ascertain their structures.

4. Chemical sysnthesis based on physiological and pathological aspects. For example, fluorouracil, a potent antimetabolite and anti-cancer agent. It is synthesized by substituting the 5th hydrogen atom with fluorine atom in the structure of uracil according to physiological property of uracil.

MtoZ Biolabs provides an extensive preclinical drug R&D platform for the screening and identification of APIs. Our team is equipped to screen and identify APIs from various sources, employing LC-MS/MS technology to analyze the compound spectra of bulk drugs among others. These spectra are then compared and analyzed against a standard product database, enabling the preliminary identification of known compounds in bulk pharmaceuticals and biological samples.

MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.

MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.

Email: marketing@mtoz-biolabs.com