MiraVista Veterinary Diagnostics
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- Beta-D-Glucan Antigen Test
Beta-D-Glucan Antigen Test
Clinical Significance: The Fungitell® assay measures the presence of (1→3)-β-D-Glucan in serum and CSF. Serum is the only specimen type cleared by the FDA for this assay. Performance characteristics of CSF have been validated by MiraVista Diagnostics.
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Methodology
Colorimetric Fungitell® assay utilizing a (1→3)-β-D-Glucan -specific Limulus Amebocyte Lysate (LAL) reagent.
Limitations
Interfering Substance: Turbid or grossly discolored samples due to lipid, bilirubin, or hemolysis. Significantly elevated immunoglobulin concentrations.
Cross Reactivity/False Positive:
- Hemodialysis
- Penicillin antibiotics
- Fractionated blood products (serum albumin and immunoglobulins)
- Specimens exposed to gauze or paper wipes
Turnaround Time
Testing is performed Monday – Friday.
Results released: 24 – 48 hours
Reference Range
None detected
Interpretative Information
Negative: <60 pg/mL
Indeterminate: 60 pg/mL – 79 pg/mL
Positive: 80 pg/mL – >500 pg/mL
Additional Information
* Fungitell® is a registered trademark of Associates of Cape Cod Inc.