MiraVista Veterinary Diagnostics

Beta-D-Glucan Antigen Test

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Clinical Significance: The Fungitell® assay measures the presence of (1→3)-β-D-Glucan in serum and CSF. Serum is the only specimen type cleared by the FDA for this assay. Performance characteristics of CSF have been validated by MiraVista Diagnostics.
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Methodology

Colorimetric Fungitell® assay utilizing a (1→3)-β-D-Glucan -specific Limulus Amebocyte Lysate (LAL) reagent.

Limitations

Interfering Substance: Turbid or grossly discolored samples due to lipid, bilirubin, or hemolysis. Significantly elevated immunoglobulin concentrations.

Cross Reactivity/False Positive:
  • Hemodialysis
  • Penicillin antibiotics
  • Fractionated blood products (serum albumin and immunoglobulins)
  • Specimens exposed to gauze or paper wipes
Turnaround Time

Testing is performed Monday – Friday.

Results released:  24 – 48 hours

Reference Range

None detected

Interpretative Information

Negative<60 pg/mL
Indeterminate60 pg/mL – 79 pg/mL
Positive: 80 pg/mL – >500 pg/mL

Additional Information

* Fungitell® is a registered trademark of Associates of Cape Cod Inc.