Bioinformatics Consultancy Services
How Our Bioinformatics Services / Bioinformatics Consultancy Can Help You? Mostly all clinical research projects give researchers with unsettling work of data (proteomics, genomics and chemicals) collection, integration and analysis. Over the last 9 years, RASA Bioinformatic CRO Lab as bioinformatics services provider or bioinformatics consultancy division has been successfully leading researchers and scientists in meeting their goals in research and development.Our client-base for Bioinformatics services or Bioinformatics Consultancy are from India as well as overseas.
Rasa’s variant-calling data analysis services along with simple variant analysis; compares multiple variant calling pipelines based on positive predictive value; (PPV; also known as precision) and sensitivity (also known as recall) for a single sequence data set.
Importantly, results from the variant-calling data analysis services can indicate significant variation across the pipelines, suggesting the need for a further detailed analysis. Rasa’s variant-calling data analysis services consists of two phase: First, previous studies are used for analyzing only a single data set. Thus, data-specific effects will not be excluded. Second, these studies specifically measures PPV and sensitivity, separately, to benchmark performance. Thus, a difference in false positive rate between high score variants and low score variants is not reflected in a single bench marking score, such as, the area under a precision-recall curve (APR), which reflects the intrinsic trade-off between precision (i.e., PPV) and recall (i.e., sensitivity), providing a more informative performance score.
SNP Calling
SNP calling is a bit of a misnomer, as it implies finding “SNPs” in NGS data. Without information about population frequency or function, it is premature to call a single nucleotide change a “polymorphism“. With that caveat in mind, “SNP calling” in the context of NGS data analysis can be defined as the process of finding bases in the NGS data that differ from the reference genome, typically including an associated confidence score or statistical evidence metric. The details of this analysis vary somewhat by application, but an early and still applicable description can be found in many research papers as well describing the MAQ alignment and variant calling algorithm which is the major consideration in our variant-calling data analysis services
- 100% Post Service Assistance
- We at RASA connect with our clients not only pre service or during service but also,after the service is delivered.
Data Security
- We assured highly secured data management and work environment.
Quality Assurance
- Our service aims at perfection and we deliver what is promised. We assure for quality assured services.
Experienced Team
- Experienced portfolio management capabilities.
Service Customization
- Apart from the package of services provided by us, we also customize service for our clients.
Free Services Training
- We not only aim at delivering services but also provide onsite training on the services to the respective clients.
Copy Number Variation (CNV) and balanced rearrangements such as inversions and translocations are types of the large structural variations in the human genome and other organisms. In Copy Number Variation, a gene or a genomic region appears in different number of copies in different individuals or even in different cells of the same individual. CNVs are generally referred to as a duplication or deletion of a genomic region with at least 1kb in length. However, several clinically important CNVs are shorter than 1 kb in length. CNV results in having variations in the gene expressions and abnormalities in the human phenotypes. Moreover, in variant-calling data analysis services CNV identified is envisaged to be associated with many human diseases such as autoimmune disease, autismand developmental disabilities, diabetes, schizophrenia, cancer, obesity and many more.