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SomaGenics - Chronic Wound Healing Program Services
SomaGenics’ wound healing program addresses the pressing unmet medical need for the effective treatment of chronic wounds, most commonly, diabetic foot ulcers (DFUs). Close to 25% of patients with diabetes develop foot ulcers with nearly 12% leading to amputation. Current standard of care therapy is not effective and treatment usually requires costly extended hospital stays. There is an immediate need for novel therapeutic strategies.
SomaGenics’ proprietary combination sshRNA-and antimiR- based therapy targets the hypoxia response pathway which is critical to normal wound healing. In patients with diabetes this pathway is defective and contributes to the impaired wound healing. SomaGenics’ novel strategy targets multiple parts of the hypoxia pathway enhancing efficacy
Using layer-by-layer technology our combination therapeutic is formulated into a slow-release, degradable bandage that can be applied directly to the wound site. In collaboration with Stanford University, we have demonstrated the ability of our combination therapy to accelerate wound healing in diabetic mice. In these preclinical animal studies the time to wound closure was significantly improved.
SomaGenics’ wound healing therapeutic approach is applicable to non-diabetic indications such as scar reduction and burn treatment. Please inquire for more information, or if interested in collaboration or other partnering opportunities.