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Isotype Controls
FromCreative Biolabs
An isotype control is an antibody that does not bind to the antigen, but has similar properties to the primary antibody used in the application. Isotype controls can be utilized as the negative control to help differentiate non-specific background signal from the specific antibody signal. Including isotype controls in some experiments, such as Flow cytometry (FC), Immunohistochemistry (IHC), is important and necessary to improve the experimental operation and data analysis.
https://viroantibody.creative-biolabs.com/category-isotype-controls-367.htm