Marker Gene Analysis Services
Unlock detailed insights into microbial communities with our specialized Marker Gene Analysis (MGA, or amplicon sequencing, services. By targeting specific genomic regions—such as the 16S rRNA gene for bacteria and archaea or the ITS regions for fungi—we provide high-resolution taxonomic classifications and relative abundance estimations within your samples.
Our Expertise in Marker Gene Analysis
At Cmbio, we leverage advanced next-generation sequencing (NGS) technologies, including long-read platforms like Oxford Nanopore Technologies (ONT), to ensure comprehensive identification of microorganisms. Our optimized workflows and expert analysis deliver accurate and in-depth microbial profiles, empowering your research with reliable data.
Our Marker Gene Analysis Services
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Customized Target Regions: We focus on variable regions of the 16S rRNA gene (e.g., V1-V8 for bacteria, V4-V9 for archaea) and can employ cross-domain primers to detect bacteria, archaea, and eukaryotes simultaneously.
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Advanced Taxonomic Classification: Utilizing databases such as SILVA, HOMD, and MiDAS, we tailor classifications to your sample type, potentially extending down to the species level. We can also accommodate alternative or custom databases to meet specific project requirements.
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Interactive Data Exploration: Gain access to our user-friendly platform for interactive exploration and visualization of your results. Features include filtering options, multivariate statistics, and customizable visualizations like heatmaps and PCA plots.
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Flexible and Scalable Solutions: Our services are designed to be cost-effective and scalable, making them suitable for continuous process monitoring, large cohort studies, and as a pre-screening tool for extensive metagenomic projects.
Amplicon Sequencing Services & Solutions
Amplicon Sequencing has been an integral methodology for microbiologists and microbiome researchers for decades; enabling the generation of whole community analysis of bacteria or fungi in any complex sample. Like many metagenomic approaches, amplicon sequencing offers unique advantages to microbiome researchers, many of which are highlighted on this page. With our targeted sequencing, you can submit complex samples and receive whole genome sequencing information, benefit from our tools used to analyze genetic variation and use data from our improved sequencing depth. Use our services to target various regions of interest. The Cmbio team have extensive experience in supporting the design and execution of amplicon-based metagenomics projects for both industry and academia for a wide range of applications, using both human and non-human sample types.