MtoZ Biolabs - Model metabolic-flux-analysis - Metabolic Flux Analysis Service
Metabolic flux analysis (MFA) is a critical technique for examining the production and consumption rates of metabolites in biological systems. In systems metabolic engineering, MFA helps understand cell physiology under specific conditions and predict metabolic capacities of cells following genetic or environmental changes. MFA is also used to elucidate cellular mechanisms. By using stable isotope labeling (such as H, C, and N), MFA can track isotopic labels along metabolic pathways, thereby identifying and quantifying the roles of these pathways. Methods such as H and C NMR, along with mass spectrometry, are commonly used in MFA. Tandem mass spectrometry, a newer technique, offers high-resolution quantification of metabolic fluxes in complex biological systems.21315213
Guo, W. et al. Bioengineering (Basel). 2015.
MtoZ Biolabs offers a MFA platform that analyzes control structures and regulatory networks of metabolic pathways. This platform is suitable for any metabolic system that can be established by kinetic models.
1. Experimental Design: We provide customized experimental designs based on your research subjects and objectives.
2. Sample Analysis: We offer various analyses of metabolic fluxes, including glucose metabolic flux, glutamine flux, and tricarboxylic acid cycle (TCA cycle) metabolic flux.
3. Data Analysis: Our metabolomics analysis includes processing mass spectrometry raw data, analyzing the data, quantifying the results, and interpreting the outcomes.
MtoZ Biolabs delivers reliable, rapid, and cost-effective MFA services, leveraging high stability, repeatability, and sensitivity systems for separation, characterization, identification, and quantification of MFA.
MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.
MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.
Email: marketing@mtoz-biolabs.com