MtoZ Biolabs - Model metabolomics-bioinformatic-analysis - Metabolomics Bioinformatic Analysis Service
The high-throughput methods employed in metabolomics generate substantial amounts of metabolic analysis data, necessitating the use of bioinformatics techniques for its processing. Bioinformatics experts at MtoZ Biolabs are capable of performing thorough and comprehensive analyses of metabolomics data. Beginning with raw mass spectrometry data, they conduct peak alignment, retention time correction, and peak area extraction. Metabolite structure identification is performed using accurate mass matching (within 25 ppm) and secondary spectrum matching in the METLIN and HMDB databases. During comparative analysis of two groups, ion peaks with more than 50% missing values in both groups are excluded. The data is subsequently normalized using autoscaling or the UV method. For statistical analysis, MtoZ Biolabs employs MetaboAnalysis and SIMCA-P software to carry out both multivariate and univariate analyses, including PCA, PLS-DA, OPLS-DA, and pathway enrichment analysis. This approach ensures the delivery of comprehensive and precise metabolomics analysis results.
1. Quality Assessment of Metabolomics Data
2. Principal Component Analysis (PCA)
3. PLS-DA/OPLS-DA 2D Diagram
4. Data Normalization Analysis
5. Univariate Statistical Analysis
6. Cluster Analysis of Differential Metabolites
7. KEGG Differential Metabolite Pathway Analysis
MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.
MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.
Email: marketing@mtoz-biolabs.com