MtoZ Biolabs - Model omega6-fatty-acids-analysis - ω-6 Fatty Acid Analysis Service

Polyunsaturated fatty acids (PUFAs) are primarily classified into ω-3 and ω-6 fatty acids. The difference between these two fatty acids lies in the position of the first double bond from the methyl end of the fatty acid chain. ω-6 fatty acids have a carbon-carbon double bond at the n-6 position.

There is competition between ω-6 and ω-3 fatty acids for desaturation enzymes. Fatty acid desaturase 1 (FADS1) and fatty acid desaturase 2 (FADS2) show a preference for α-linolenic acid (ALA) over linoleic acid (LA). However, high intake of LA, typical in Western diets, interferes with the desaturation and elongation of ALA. Similarly, trans fatty acids disrupt the desaturation and elongation of both LA and ALA.

ω-6 and ω-3 fatty acids are metabolically and functionally distinct and cannot be interconverted. They often have opposing physiological roles and are crucial in dietary balance. An elevated ω-6/ω-3 ratio is pro-inflammatory, contributing to atherosclerosis, obesity, and diabetes through gene expression changes, prostaglandin and leukotriene metabolism, and interleukin-1 production. High ω-6 intake promotes insulin resistance, while ω-3 intake supports homeostasis and weight loss.

Free project evaluation!MtoZ Biolabs offers reliable, rapid, and cost-effective ω-6 fatty acids analysis services based on high-stability, reproducible, and high-sensitivity separation, characterization, identification, and quantification systems.

1. Linoleic acid (LA) 18 : 2 (n-6)

2. Gamma-linolenic acid (GLA) 18 : 3 (n-6)

3. Dihomo-gamma-linolenic acid (DGLA) 20 : 3 (n-6)

4. Arachidonic acid (AA, ARA) 20 : 4 (n-6)

MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.

MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.

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