Protein Expression Services

Aviva recombinant protein expression in E. coli includes antigen production, ligand preparation, and proteins for binding assays, cell based assays, enzymatic assays, and assays for vaccine and therapeutic development. Our proprietary platforms can produce functional recombinant proteins, domain specific fragments, fusion proteins, and protein complexes. We understand the need for active proteins, free of impurities, to produce clean reproducible results.

View our ISO13485 compliant protein development, validation, and production options.

Aviva mammalian expression systems generate high-yields of mammalian proteins. These expression systems are often suggested for proteins requiring mammalian post-translational modifications. Aviva has a great amount of experience producing monoclonal antibodies or recombinant proteins from a wide range of cell types including CHO, hybridomas, various mouse myeloma, and human cell lines. Aviva performs a comprehensive analysis of your project in order to identify the best expression platforms with appropriate scalability, yield, and functionality. Our service includes bioinformatics analysis, domain selection, vector design, tag selection, sequence confirmation, cell transfection, cell amplification, purification by tag selection, yield optimization, scale up processing, and protein characterization.

View our ISO13485 compliant protein development, validation, and production options.

Aviva`s yeast expression platform provides a flexible, controllable, and effective solution for protein expression needs. Aviva`s various yeast expression platforms have been well characterized and are validated to perform many post-translational modifications. Aviva offers an initial assessment of your project and makes recommendations regarding expression platforms with appropriate scalability, yield, and functionality. Our approach includes bioinformatics analysis, domain selection, vector design, tag selection, sequence confirmation, cell transfection, cell amplification, purification by tag selection, yield optimization, scale up processing, and protein characterization.

View our ISO13485 compliant protein development, validation, and production options.

One of the determining factors in quality antibody development is quality antigen preparation. We focus on preparation of high-quality antigen for ensuring high-quality antibody development.

• Using our bioinformatics core we determine the best immunogenic domain for antibody generation.
• Using our proprietary fusion domain and vectors we express and purify recombinant antigens in the most cost-effective manner.
• Aviva can provide full services, with the customer providing a target protein accession number and Aviva delivering high-quality polyclonal or monoclonal antibodies.

There are different natures and great variations of antigens in type, form, size, availability, etc. Each type of antigen has its own utility, advantages and disadvantages.