Karius, Inc.

Rapid Liquid Biopsy for Infectious Disease

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The Karius Test is a liquid biopsy that can non-invasively and rapidly detect over 1000 pathogens causing both deep-seated and bloodstream infections from a single blood sample. The Karius Test helps clinicians avoid invasive, low-yield, and sequential diagnostic tests that can delay treatment for the most vulnerable hospitalized patients.

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The main clinical application for the Karius Test is to help physicians diagnose infections in immunocompromised patients

  • Invasive Fungal Infections
  • Endocarditis
  • Infectious Causes of Neutropenic Fever
  • Pneumonia
  • Opportunistic Infections
The Karius Test improves diagnosis and management of life-threatening infections

Reduce complications from invasive procedures with 1 blood sample

The Karius Test requires 1 single blood draw to reveal information-rich, microbial cell–free DNA, potentially avoiding 63% of invasive diagnostic procedures.

Speed up diagnosis of infections with a 1-day turnaround time

The Karius Test results typically report the next day after sample receipt, compared to standard methods, which can take days or weeks to yield results.

Optimize antimicrobial treatment

The Karius Test results have led to a change in antimicrobial management in 59%-75% of cases.