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MtoZ BiolabsModel analysis-of-molecular-size-variation-based-on-sec - SEC Based Molecular Size Variation Analysis Service

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Molecular size variation critically influences the properties of biomacromolecules such as proteins, antibodies, and peptides, especially in the realms of drug research and bioproduct manufacturing. Size Exclusion Chromatography (SEC), also known as Gel Permeation Chromatography (GPC), separates compounds based on molecular size.
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Molecular size variability critically influences the properties of biomacromolecules such as proteins, antibodies, and peptides, especially in the realms of drug research and bioproduct manufacturing. Size exclusion chromatography (SEC), also known as gel permeation chromatography (GPC), separates compounds based on molecular size. This method leverages the size exclusion effect of column packing pores, allowing molecules of different sizes to traverse the chromatography column at varying rates to achieve separation. The relative molecular size of the sample is estimated by comparing the elution order of the sample with standard proteins of known size.

The SEC-based molecular size variability analysis at MtoZ Biolabs offers insights into the size, molecular weight, and distribution of molecules in samples, serving as an essential tool in drug quality control, vaccine development, and enzyme activity studies. Leveraging an advanced SEC system and high-sensitivity detectors, MtoZ Biolabs has developed an efficient analysis platform to provide thorough and accurate SEC molecular size variability analyses. With expert data processing and interpretation, this platform ensures that all quality aspects of protein or peptide products are met during both research and production phases. MtoZ Biolabs swiftly delivers comprehensive solutions and data support for all molecular forms, from high molecular weight aggregates and medium molecular weight target proteins to low molecular weight degradation products.


In the technical report, MtoZ Biolabs will provide you with detailed technical information, including:

1. Experimental Procedures

2. Relevant Experimental Parameters

3. Detailed Information on SEC-Based Molecular Size Variability Analysis

4. Electrophoresis Images

5. Raw Data


MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.

MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.

Email: marketing@mtoz-biolabs.com