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Small Molecule Activators

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Enzymes are macromolecules with biocatalytic function to accelerate chemical reactions. Enzymes are indispensable in various functions of living organisms and play key roles in almost every physiological/pathological process such as signal transduction, cell regulation, metabolism, activity control and digestion. Strict control of enzyme activity is essential for homeostasis. Any malfunction of key enzymes (mutation, overproduction, underproduction or deletion) can lead to diseases. Therefore, enzymes have long been considered as important drug targets for the treatment of major human diseases.